2005

Shared and Unique Functions of the DExD/H-box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity

Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T.
J Immunol. 2005 Sep 1;175(5):2851-8. doi: 10.4049/jimmunol.175.5.2851.

Reemergence of Hepatitis C Virus After 8.5 Years in a Patient With Hypogammaglobulinemia: Evidence for an Occult Viral Reservoir

Lee WM, Polson JE, Carney DS, Sahin B, Gale M Jr.
J Infect Dis. 2005 Sep 15;192(6):1088-92. doi: 10.1086/432917.

Evasion of Intracellular Host Defence by Hepatitis C Virus

Gale M Jr, Foy EM.
Review: Nature. 2005 Aug 18;436(7053):939-45. doi: 10.1038/nature04078.

Identification of FBL2 as a Geranylgeranylated Cellular Protein Required for Hepatitis C Virus RNA Replication

Wang C, Gale M Jr, Keller BC, Huang H, Brown MS, Goldstein JL, Ye J.
Mol Cell. 2005 May 13;18(4):425-34. doi: 10.1016/j.molcel.2005.04.004.

GB Virus Type C NS5A Sequence Polymorphisms: Association With Interferon Susceptibility and Inhibition of PKR-mediated eIF2alpha Phosphorylation

Xiang J, Martinez-Smith C, Gale M Jr, Chang Q, Labrecque DR, Schmidt WN, Stapleton JT..
J Interferon Cytokine Res. 2005 May;25(5):261-70. doi: 10.1089/jir.2005.25.261.

The Oncogenic Potential of Hepatitis C Virus NS5A Sequence Variants Is Associated With PKR Regulation

Giménez-Barcons M, Wang C, Chen M, Sánchez-Tapias JM, Sáiz JC, Gale M Jr.
J Interferon Cytokine Res. 2005 Mar;25(3):152-64. doi: 10.1089/jir.2005.25.152.

Distinct poly(I-C) and Virus-Activated Signaling Pathways Leading to Interferon-Beta Production in Hepatocytes

Li K, Chen Z, Kato N, Gale M Jr, Lemon SM.
J Biol Chem. 2005 Apr 29;280(17):16739-47. doi: 10.1074/jbc.M414139200. Epub 2005 Feb 28.

Control of Antiviral Defenses Through Hepatitis C Virus Disruption of Retinoic Acid-Inducible gene-I Signaling

Foy E, Li K, Sumpter R Jr, Loo YM, Johnson CL, Wang C, Fish PM, Yoneyama M, Fujita T, Lemon SM, Gale M Jr.
Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2986-91. doi: 10.1073/pnas.0408707102. Epub 2005 Feb 14.

Immune Evasion by Hepatitis C Virus NS3/4A Protease-Mediated Cleavage of the Toll-like Receptor 3 Adaptor Protein TRIF

Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr, Lemon SM.
Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2992-7. doi: 10.1073/pnas.0408824102. Epub 2005 Feb 14.

Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication Through a Cellular RNA Helicase, RIG-I

Sumpter R Jr, Loo YM, Foy E, Li K, Yoneyama M, Fujita T, Lemon SM, Gale M Jr.
J Virol. 2005 Mar;79(5):2689-99. doi: 10.1128/JVI.79.5.2689-2699.2005.