2010

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members.

Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, Buller RM, Gale M Jr, Shi PY, Diamond MS.

Nature. 2010 Nov 18;468(7322):452-6. doi: 10.1038/nature09489. PMID: 21085181

The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system.

Szretter KJ, Daffis S, Patel J, Suthar MS, Klein RS, Gale M Jr, Diamond MS.

J Virol. 2010 Dec;84(23):12125-38. doi: 10.1128/JVI.01026-10. Epub 2010 Sep 29. PMID: 20881045

RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP.

Malathi K, Saito T, Crochet N, Barton DJ, Gale M Jr, Silverman RH.

RNA. 2010 Nov;16(11):2108-19. doi: 10.1261/rna.2244210. Epub 2010 Sep 10. PMID: 20833746

IPS-1 is essential for the control of West Nile virus infection and immunity.

Suthar MS, Ma DY, Thomas S, Lund JM, Zhang N, Daffis S, Rudensky AY, Bevan MJ, Clark EA, Kaja MK, Diamond MS, Gale M Jr.

PLoS Pathog. 2010 Feb 5;6(2):e1000757. doi: 10.1371/journal.ppat.1000757. PMID: 20140199

Recognition of viruses by cytoplasmic sensors.

Wilkins C, Gale M Jr.

Curr Opin Immunol. 2010 Feb;22(1):41-7. doi: 10.1016/j.coi.2009.12.003. Epub 2010 Jan 12. Review. PMID: 20061127