2011

Inhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

Perwitasari O, Cho H, Diamond MS, Gale M Jr.
J Biol Chem. 2011 Dec 30;286(52):44412-23. doi: 10.1074/jbc.M111.285205. Epub 2011 Nov 7. PMID: 22065572

RIG-I like receptors in antiviral immunity and therapeutic applications.

Ireton RC, Gale M Jr.
Viruses. 2011 Jun;3(6):906-19. doi: 10.3390/v3060906. Epub 2011 Jun 23. Review. PMID: 21994761

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity.

Ramos HJ, Gale M Jr.
Curr Opin Virol. 2011 Sep;1(3):167-76. doi: 10.1016/j.coviro.2011.04.004. Review. PMID: 21949557

Structural basis of RNA recognition and activation by innate immune receptor RIG-I.

Jiang F, Ramanathan A, Miller MT, Tang GQ, Gale M Jr, Patel SS, Marcotrigiano J.
Nature. 2011 Sep 25;479(7373):423-7. doi: 10.1038/nature10537. PMID: 21947008

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection.

Brien JD, Daffis S, Lazear HM, Cho H, Suthar MS, Gale M Jr, Diamond MS.
PLoS Pathog. 2011 Sep;7(9):e1002230. doi: 10.1371/journal.ppat.1002230. Epub 2011 Sep 1. PMID: 21909274

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus.

Horner SM, Liu HM, Park HS, Briley J, Gale M Jr.
Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14590-5. doi: 10.1073/pnas.1110133108. Epub 2011 Aug 15. PMID: 21844353

Immune signaling by RIG-I-like receptors.

Loo YM, Gale M Jr.
Immunity. 2011 May 27;34(5):680-92. doi: 10.1016/j.immuni.2011.05.003. Review. PMID: 21616437

Beta interferon controls West Nile virus infection and pathogenesis in mice.

Lazear HM, Pinto AK, Vogt MR, Gale M Jr, Diamond MS.
J Virol. 2011 Jul;85(14):7186-94. doi: 10.1128/JVI.00396-11. Epub 2011 May 4. PMID: 21543483

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production.

Harman AN, Lai J, Turville S, Samarajiwa S, Gray L, Marsden V, Mercier SK, Jones K, Nasr N, Rustagi A, Cumming H, Donaghy H, Mak J, Gale M Jr, Churchill M, Hertzog P, Cunningham AL.
Blood. 2011 Jul 14;118(2):298-308. doi: 10.1182/blood-2010-07-297721. Epub 2011 Mar 16. Erratum in: Blood. 2011 Dec 22;118(26):6992. Mercier, Sarah [corrected to Mercier, Sarah K]. PMID: 21411754

HCV Regulation of Host Defense.

Carney DS, Gale M Jr..
In: Tan SL, editor. Hepatitis C Viruses: Genomes and Molecular Biology. Norfolk (UK): Horizon Bioscience; 2006. Chapter 13. PMID: 21250381

Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses.

Giordano D, Li C, Suthar MS, Draves KE, Ma DY, Gale M Jr, Clark EA.
J Leukoc Biol. 2011 Mar;89(3):443-55. doi: 10.1189/jlb.0610329. Epub 2010 Dec 22. PMID: 21178115

ZAPS electrifies RIG-I signaling.

Liu HM, Gale M Jr.
Nat Immunol. 2011 Jan;12(1):11-2. doi: 10.1038/ni0111-11. No abstract available. PMID: 21169998

Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine.