Gale Lab is partnering with Dr. Ralph Baric and Dr. Mark Heise of the University of North Carolina at Chapel Hill, and others, to develop new--genetically defined mouse models to mechanistically define the role of specific polymorphic genes and sets of genes in differentially regulating targeted immune responses.

Individual Research Projects

Project 1:  System Immunogenetics of SARS-CoV Infection
                   Dr. Ralph S. Baric, Professor Department of Epidemiology, UNC Chapel Hill

Project 2:  System Immunogenetics of Influenza-Induced Innate & Adaptive Immunity in the Lung
                   Dr. Mark Heise, Assistant Professor of Genetics, School of Medicine, UNC Institute for Global Health & Infectious Diseases

Project 3:  System Immunogenetics of Innate Immune and Inflammatory Responses to West Nile Virus Infection
                   Dr. Michael Gale, Jr.

Project 4:  System Immunogenetics of West Nile Virus Infection: Adaptive Immunity 
                   Dr. Jennifer Lund

Cores

Core A:  Administrative and Education Core
               Dr. Ralph S. Baric, Professor Department of Epidemiology, UNC Chapel Hill

Core B:  Animal Models Core
               Dr. Fernando Pardo-Manuel de Villena, Interim Chair, Professor, UNC Chapel Hill

Core C:  High-Throughput Molecular Profiling Core

Core D:  Systems Immunogenetics Core
               Dr. Shannon McWeeney, OHSU

Core E:  Bioinformatics Core